Impact of IL-28B polymorphism on outcome in patients with hepatitis C after liver transplantation.

摘要

Hepatitis C is often complicated by the development of cirrhosis and hepatocellu-lar carcinoma. In Europe, the prevalence of hepatitis C virus (HCV) infection is approximately 1.5%. If a HCV infection is not treated or ineffectively treated, hepato-cellular function may deteriorate progressively [l]. For patients with end-stage disease, liver transplantation (LT) is currently the treatment of choice [2]. The course of hepatitis C in a graft after LT is usually more severe than the course of hepatitis C in nontransplant patients [2].