INCIDENCE OF CYTOMEGALOVIRUS (CMV) RETINITIS IN SECOND EYES OF PATIENTS WITH THE ACQUIRED IMMUNE DEFICIENCY SYNDROME AND UNILATERAL CMV RETINITIS

摘要

Research Objective To evaluate the risk and risk factors for developing cytomegalovirus (CMV) retinitis in previously uninvolved second eyes among patients with unilateral CMV retinitis. Study Design Cohort study. Location The Johns Hopkins University, Baltimore, MD. Funding Source Grants from the National Institutes of Health. Relevant Methodology A total of 376 consecutive patients with AIDS and unilateral CMV retinitis were followed from the time of CMV retinitis diagnosis for the development of second-eye retinitis. Demographic and clinical characteristics were noted at baseline. Use of highly active antiretroviral therapy (HAART) and immune recovery in response to HAART were noted prospectively.