Preliminary study on biological and physical properties of new surgical threads for soft tissues.

摘要

The aim of the study was to evaluate the physical and biological properties of new surgical threads provided by Matcur, S.A. De C.V., Mexico. The study was performed on 12 Polish Large White piglets, divided into two equal groups and subjected to surgical procedures at the age of 40 days. The first group of animals (control group) was subjected to a sham operation, whereas the experimental group had undergone gastric fundectomy. The fundectomy consisted of cutting out the fundus of the stomach. The soft tissues of the fundectomised stomach were sutured, using catgut quirurgico simple and catgut quirurgico cromico threads. The sham operation consisted of cutting through soft tissues of the abdominal region, which enabled access to the anatomical structures of the stomach, analogically to the experimental group. During the operation procedure, the threads were assessed for the needle penetration and ability to pass through tissues, the tendency to electrify, twisting ability, elasticity, knot stability and tendency to soak up tissue fluids. The mechanical properties of the threads were investigated using an extension test in Lloyd LRX testing machine. Furthermore, haematological and biochemical analyses of the serum were performed 60 d after the surgery. The obtained results showed very high surgical reliability of the investigated threads with no side effects in any of the experimental animals. The wound healing process was characterised by minimal reaction of the soft tissues. The extension test showed very high mechanical endurance of the investigated threads. Moreover, positive results were obtained after the evaluation of knot stability of the threads. Decreased values of haemoglobin, haematocrit, and daily body weight gain of the animals from the experimental group were observed as negative consequences of the fundectomy..