The involvement of IgH enhancer HS1.2 in the pathogenesis of Crohn's disease: how the immune system can influence a multifactorial disease

Cianci R.; Lolli S.; Pagliari D.; Gambassi G.; Frosali S.; Marmo R.; Melioli G.; Orlando A.; Newton E. E.; Serone E.; Landolfi R.; Pandolfi F.; Frezza D.

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The involvement of IgH enhancer HS1.2 in the pathogenesis of Crohn's disease: how the immune system can influence a multifactorial disease

机译：IgH增强剂HS1.2参与克罗恩病的发病机理：免疫系统如何影响多因素疾病

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OBJECTIVE: To study the 3' immunoglobulin heavy-chain regulatory region (3' RR) enhancer complex, active in class switching recombination and in B-cells, in Crohn's disease.

机译：目的：研究克罗恩病中3类免疫球蛋白重链调节区（3′RR）增强子复合物，该复合物在类转换重组和B细胞中具有活性。

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来源
《European review for medical and pharmacological sciences.》 |2016年第17期|共10页
作者
Cianci R.; Lolli S.; Pagliari D.; Gambassi G.; Frosali S.; Marmo R.; Melioli G.; Orlando A.; Newton E. E.; Serone E.; Landolfi R.; Pandolfi F.; Frezza D.;
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正文语种 eng
中图分类药理学;
关键词
Crohn's disease; IgH Enhancer hs1.2; Immunoglobulins; Anti-Saccharomyces cerevisiae antibodies (AS-CA); Dysbiosis;

机译：克罗恩病;IgH增强剂hs1.2;免疫球蛋白;抗酿酒酵母抗体（AS-CA）;铁血病;

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1. The involvement of IgH enhancer HS1.2 in the pathogenesis of Crohn's disease: how the immune system can influence a multifactorial disease [J] . Cianci R., Lolli S., Pagliari D., European review for medical and pharmacological sciences. . 2016,第17期

机译：IgH增强剂HS1.2参与克罗恩病的发病机理：免疫系统如何影响多因素疾病
2. Immune System Involvement in the Pathogenesis of JC Virus Induced PML: What is Learned from Studies of Patients with Underlying Diseases and Therapies as Risk Factors [J] . Maria Chiara G. Monaco, Eugene O. Major Frontiers in Immunology . 2015,第10期

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3. Intestinal Microbiota and the Innate Immune System – A Crosstalk in Crohn’s Disease Pathogenesis [J] . Lea-Maxie Haag, Britta Siegmund Frontiers in Immunology . 2015,第12期

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4. State-of-the Art Lecture:The multifactorial pathogenesis of inflammatory bowel disease [C] . C. FIOCCH Falk Symposium . 2007

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5. Best Practice for Screening Adult Patients with Psoriasis for Polyautoimmunity: Celiac Disease, Rheumatoid Arthritis and Crohn's Disease [D] . Ashbaugh, Susan Danielle. 2017

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6. Immune System Involvement in the Pathogenesis of JC Virus Induced PML: What is Learned from Studies of Patients with Underlying Diseases and Therapies as Risk Factors [O] . Maria Chiara G. Monaco, Eugene O. Major 2015

机译：免疫系统参与JC病毒诱导的PML发病机理：从作为疾病危险因素的基础疾病和疗法患者的研究中了解到
7. Immune system involvement in the pathogenesis of JC Virus induced PMLWhat is learned from studies of patients with underlying diseases and therapies as risk factors. [O] . Maria Chiara G Monaco, Eugene O Major 2015

机译：免疫系统参与JC病毒诱导pmL的发病机制从基础疾病和治疗作为风险因素的患者的研究中获知。

The involvement of IgH enhancer HS1.2 in the pathogenesis of Crohn's disease: how the immune system can influence a multifactorial disease

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