Effects of osteopontin on the expression of IL-6 and IL-8 inflammatory factors in human knee osteoarthritis chondrocytes

Yang Y.; Gao S. -G.; Zhang F. -J.; Luo W.; Xue J. -X.; Lei G. -H.

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Effects of osteopontin on the expression of IL-6 and IL-8 inflammatory factors in human knee osteoarthritis chondrocytes

机译：骨桥蛋白对人膝骨关节炎软骨细胞IL-6和IL-8炎性因子表达的影响

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OBJECTIVE: Osteoarthritis (OA) is a chronic musculoskeletal disease characterized by progressive destruction of articular cartilage, OA lead to chronic pain and functional restrictions in affected joints. The present study was to investigate the role of osteopontin (OPN) in the athogenesis of OA through studying the effect of OPN on expression of IL-6 and IL-8 inflammatory factors in human OA chondrocytes.

机译：目的：骨关节炎（OA）是一种慢性肌肉骨骼疾病，其特征是关节软骨逐渐受到破坏，OA导致慢性疼痛和受影响关节的功能受限。本研究旨在通过研究骨桥蛋白（OPN）对人OA软骨细胞中IL-6和IL-8炎性因子表达的影响来研究骨桥蛋白（OPN）在OA的非人类活动中的作用。

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《European review for medical and pharmacological sciences.》 |2014年第23期|共7页
作者
Yang Y.; Gao S. -G.; Zhang F. -J.; Luo W.; Xue J. -X.; Lei G. -H.;
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原文格式 PDF
正文语种 eng
中图分类药理学;
关键词
Osteoarthritis (OA); Osteopontin (OPN); Chondrocytes; Interleukin-6 (IL-6); Interleukin-8 (IL-8);

机译：骨关节炎（OA）;骨桥蛋白（OPN）;软骨细胞;白介素6（IL-6）;白介素8（IL-8）;

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1. RETRACTED ARTICLE: Effects of Osteopontin on Expression of IL-6 and IL-8 Inflammatory Factors in Human Knee Osteoarthritis Chondrocytes [J] . YaoW., ChenX., LiD., Cell biochemistry and biophysics . 2014,第1期

机译：收回的文章：骨桥蛋白对人膝骨关节炎软骨细胞IL-6和IL-8炎症因子表达的影响
2. Effects of osteopontin on the expression of IL-6 and IL-8 inflammatory factors in human knee osteoarthritis chondrocytes [J] . Yang Y., Gao S. -G., Zhang F. -J., European review for medical and pharmacological sciences. . 2014,第23期

机译：骨桥蛋白对人膝骨关节炎软骨细胞IL-6和IL-8炎性因子表达的影响
3. Effects of osteopontin on the expression of IL-6 and IL-8 inflammatory factors in human knee osteoarthritis chondrocytes [J] . Y. Yang, S.-G. Gao, F.-J. Zhang, European review for medical and pharmacological sciences. . 2014,第23期

机译：骨桥蛋白对人膝骨关节炎软骨细胞IL-6和IL-8炎性因子表达的影响
4. A Novel Murine Model of Biomaterial Induced Osteolysis: Expression of the Chemokine MCP-1 and the Pro-Inflammatory Cytokines IL-1β and IL-6 [C] . Warme B., Epstein N.J., Trindade M.C.D., Annual meeting of the Society For Biomaterials . 2003

机译：一种新型的生物材料诱导骨溶解的小鼠模型：趋化因子MCP-1和促炎性细胞因子IL-1β和IL-6的表达
5. The fading athlete with an old knee: Investigation of factors and outcomes after anterior cruciate ligament injury related to the development of knee osteoarthritis. [D] . Wellsandt, Elizabeth. 2016

机译：膝盖衰老的运动员：前交叉韧带损伤与膝骨关节炎发展相关的因素和结果的调查。
6. Phosphorylation of osteopontin has proapoptotic and proinflammatory effects on human knee osteoarthritis chondrocytes [O] . Shu-Guang Gao, Yang Yu, Chao Zeng, -1

机译：骨桥蛋白的磷酸化对人膝骨关节炎软骨细胞具有促凋亡和促炎作用
7. Enhanced expression and activation of pro-inflammatory transcription factors distinguish aneurismal from atherosclerotic aorta: IL-6 and IL-8 dominated inflammatory responses prevail in the human aneurysm [O] . Lindeman, Jan HN, Abdul-Hussien, Hazem, Schaapherder, Alexander FM, 2007

机译：促炎转录因子的增强表达和激活将动脉瘤和动脉粥样硬化主动脉区分开来：IL-6和IL-8占主导的炎症反应在人类动脉瘤中占主导地位
8. Cytokine (Tumor Necrosis Factor, IL-6, and IL-8) Production by Respiratory Syncytial Virus-Infected Human Alveolar Macrophages [R] . Becker, S., Quay, J., Soukup, J. 1991

机译：呼吸道合胞病毒感染的人肺泡巨噬细胞产生细胞因子（肿瘤坏死因子，IL-6和IL-8）

Effects of osteopontin on the expression of IL-6 and IL-8 inflammatory factors in human knee osteoarthritis chondrocytes

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