PTEN Protein Loss and Clinical Outcome from Castration-resistant Prostate Cancer Treated with Abiraterone Acetate

Ferraldeschi Roberta; Rodrigues Daniel Nava; Riisnaes Ruth; Miranda Susana; Figueiredo Ines; Rescigno Pasquale; Ravi Praful; Pezaro Carmel; Omlin Aurelius; Lorente David; Zafeiriou Zafeiris; Mateo Joaquin; Altavilla Amelia; Sideris Spyridon; Bianchini Diletta; Grist Emily; Thway Khin; Lopez Raquel Perez; Tunariu Nina; Parker Chris; Dearnaley David; Reid Alison; Attard Gerhardt; de Bono Johann

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PTEN Protein Loss and Clinical Outcome from Castration-resistant Prostate Cancer Treated with Abiraterone Acetate

机译：醋酸阿比特龙治疗PTEN蛋白丢失和去势抵抗性前列腺癌的临床结果

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Background: Loss of the tumor suppressor phosphatase and tensin homolog (PTEN) occurs frequently in prostate cancers. Preclinical evidence suggests that activation of PI3K/AKT signaling through loss of PTEN can result in resistance to hormonal treatment in prostate cancer.

机译：背景：在前列腺癌中经常会发生肿瘤抑制酶磷酸酶和张力蛋白同源物（PTEN）的丢失。临床前证据表明，通过丢失PTEN激活PI3K / AKT信号传导可导致前列腺癌对激素治疗的耐药性。

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《European urology》 |2015年第4期|共8页
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Ferraldeschi Roberta; Rodrigues Daniel Nava; Riisnaes Ruth; Miranda Susana; Figueiredo Ines; Rescigno Pasquale; Ravi Praful; Pezaro Carmel; Omlin Aurelius; Lorente David; Zafeiriou Zafeiris; Mateo Joaquin; Altavilla Amelia; Sideris Spyridon; Bianchini Diletta; Grist Emily; Thway Khin; Lopez Raquel Perez; Tunariu Nina; Parker Chris; Dearnaley David; Reid Alison; Attard Gerhardt; de Bono Johann;
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正文语种 eng
中图分类泌尿科学（泌尿生殖系疾病）;
关键词
Prostate cancer; PTEN; Abiraterone acetate; Immunohistochemistry;

机译：前列腺癌;PTEN;醋酸阿比特龙;免疫组化;
入库时间 2022-08-18 10:59:33

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1. PTEN Protein Loss and Clinical Outcome from Castration-resistant Prostate Cancer Treated with Abiraterone Acetate [J] . Ferraldeschi Roberta, Rodrigues Daniel Nava, Riisnaes Ruth, European urology . 2015,第4期

机译：醋酸阿比特龙治疗PTEN蛋白丢失和去势抵抗性前列腺癌的临床结果
2. A prognostic model for stratifying clinical outcomes in chemotherapy-naive metastatic castration-resistant prostate cancer patients treated with abiraterone acetate [J] . Daniel Joseph Khalaf, Claudia M. Avilés, Arun A. Azad, Canadian Urological Association Journal . 2018,第2期

机译：醋酸阿比特龙治疗的单纯化疗转移性去势抵抗性前列腺癌患者临床预后分层的预后模型
3. NUMBER NEEDED TO TREAT AND COST PER CLINICALLY MEANINGFUL OUTCOME OF ENZALUTAMIDE AND ABIRATERONE ACETATE FOR THE TREATMENT OF METASTATIC CASTRATION-RESISTANT PROSTATE CANCER THAT FAILED ANDROGEN DEPRIVATION THERAPY IN BRAZIL [J] . Sasse A. P., Lopes G., Teich V, Value in health: the journal of the International Society for Pharmacoeconomics and Outcomes Research . 2016,第7期

机译：根据临床意义评估恩扎鲁米特和醋酸阿比特雷酮用于治疗转移性抗前列腺癌的前列腺癌的治疗和费用的数字
4. Hormone Refractory Prostate Cancer: Lessons Learned from the PTEN Prostate Cancer Model [C] . David J. Mulholland, Jing Jiao, Hong W International Symposium on Hormonal Carcinogenesis . 2008

机译：激素难治性前列腺癌：从Pten前列腺癌模型中学到的经验教训
5. The Role of BET Proteins in Castration-Resistant Prostate Cancer Dissemination [D] . Shafran, Jordan Seth. 2020

机译：Bet蛋白在抗阉割前列腺癌传播中的作用
6. PTEN Protein Loss and Clinical Outcome from Castration-resistant Prostate Cancer Treated with Abiraterone Acetate [O] . Roberta Ferraldeschi, Daniel Nava Rodrigues, Ruth Riisnaes, -1

机译：醋酸阿比特龙治疗PTEN蛋白丢失和去势抵抗性前列腺癌的临床结果
7. PTEN protein loss and clinical outcome from castration-resistant prostate cancer treated with abiraterone acetate [O] . Ferraldeschi, Roberta, Nava Rodrigues, Daniel, Riisnaes, Ruth, 2015

机译：醋酸阿比特龙治疗的去势抵抗性前列腺癌PTEN蛋白丢失和临床结局

PTEN Protein Loss and Clinical Outcome from Castration-resistant Prostate Cancer Treated with Abiraterone Acetate

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