Research on rat models of hypobaric hypoxia-induced pulmonary hypertension

Ma T. -T.; Wang Y.; Zhou X. -L.; Jiang H.; Guo R.; Jia L. -N.; Chang H.; Gao Y.; Yao X. -Y.; Gao Z. -M.; Pan L.

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Research on rat models of hypobaric hypoxia-induced pulmonary hypertension

机译：低压低氧性肺动脉高压大鼠模型的研究

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OBJECTIVE: Rat models of hypobaric hypoxia-induced pulmonary hypertension are commonly used in studies of chronic mountain sickness, while there are few researches specially focusing on these rats model. This study aims to exploring possible pathogenesis of hypobaric hypoxia-induced pulmonary hypertension by experimenting on hypobaric hypoxia-induced PH rat models at different simulate-altitudes.

机译：目的：低氧低氧引起的肺动脉高压大鼠模型常用于慢性山区疾病的研究，但很少有专门针对这些大鼠模型的研究。本研究旨在通过在不同模拟海拔高度下进行低压低氧诱导的PH大鼠模型的实验，探索低压低氧诱导的肺动脉高压的可能发病机制。

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《European review for medical and pharmacological sciences.》 |2015年第19期|共8页
作者
Ma T. -T.; Wang Y.; Zhou X. -L.; Jiang H.; Guo R.; Jia L. -N.; Chang H.; Gao Y.; Yao X. -Y.; Gao Z. -M.; Pan L.;
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正文语种 eng
中图分类药理学;
关键词
Hypobaric hypoxia; Pulmonary hypertension; Animal models;

机译：低压缺氧;肺动脉高压;动物模型;

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专利

1. Research on rat models of hypobaric hypoxia-induced pulmonary hypertension [J] . Ma T. -T., Wang Y., Zhou X. -L., European review for medical and pharmacological sciences. . 2015,第19期

机译：低压低氧性肺动脉高压大鼠模型的研究
2. Proteomic analysis of the lung in rats with hypobaric hypoxia-induced pulmonary hypertension [J] . OhataY., OgataS., NakanishiK., Histology and histopathology . 2013,第7a9期

机译：低压缺氧所致肺动脉高压大鼠肺的蛋白质组学分析
3. Expression of P2X4R mRNA and protein in rats with hypobaric hypoxia-induced pulmonary hypertension. [J] . Ohata Y, Ogata S, Nakanishi K, Circulation journal . 2011,第4期

机译：低压缺氧所致肺动脉高压大鼠P2X4R mRNA和蛋白的表达。
4. Carvedilol inhibition pf chronic hypoxia-induced pulmonary hypertension and right ventricular hypertrophy in rats [C] . Loi c Tual, Favrice Favret, Olivier-Eric Morel, World Congress on Mountain Medicine and High Altitude Physiology . 2003

机译：Carvedilol抑制PF慢性缺氧诱导的肺动脉高压和大鼠右心室肥厚
5. 4,4'-Methylenedianiline as a novel sex-specific model of pulmonary arterial hypertension in female rats [D] . Carroll Turpin, Michelle Ann-Marie 2015

机译：4,4'-亚甲基二苯胺作为雌性大鼠肺动脉高压的新型性别特异性模型
6. Effects of chrysin (57-dihydroxyflavone) on vascular remodeling in hypoxia-induced pulmonary hypertension in rats [O] . Xian-Wei Li, Xiang-Ming Wang, Shu Li, 2015

机译：chrysin（57-dihydroxyflavone）对缺氧性肺动脉高压大鼠血管重构的影响
7. Expression of P2X4R mRNA and Protein in Rats With Hypobaric Hypoxia-Induced Pulmonary Hypertension [O] . Yuichiro Ohata, Sho Ogata, Kuniaki Nakanishi, 2011

机译：P2X4R mRNA和蛋白在低次生缺氧诱导的肺动脉高压大鼠中的表达

Research on rat models of hypobaric hypoxia-induced pulmonary hypertension

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