首页> 外文期刊>European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) >Significance of serine-167 and cysteine-129 residues in the active site of the immune-suppressive enzyme indoleamine 2,3-dioxygenase 1 (IDO1) for the binding of novel inhibitors

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Significance of serine-167 and cysteine-129 residues in the active site of the immune-suppressive enzyme indoleamine 2,3-dioxygenase 1 (IDO1) for the binding of novel inhibitors

机译：免疫抑制酶吲哚胺2,3-双加氧酶1（IDO1）活性位点中丝氨酸167和半胱氨酸129残基对于新型抑制剂结合的意义

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《European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)》 |2014年第6期|共1页
作者
Tomek P.; Palmer B. D.; Flanagan J. U.; Ching L.;
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正文语种 eng
中图分类肿瘤学;
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1. 阴茎鳞状细胞癌患者吲哚胺2,3-双加氧化酶1(IDO1)表达和催化活性的上调与免疫抑制和预后不良相关 [J] . 周强华, 秦自科, 刘卓炜, 癌症（英文版） . 2020,第004期
2. Significance of serine-167 and cysteine-129 residues in the active site of the immune-suppressive enzyme indoleamine 2,3-dioxygenase 1 (IDO1) for the binding of novel inhibitors [J] . Tomek P., Palmer B. D., Flanagan J. U., European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2014,第Suppla6期

机译：免疫抑制酶吲哚胺2,3-双加氧酶1（IDO1）活性位点中丝氨酸167和半胱氨酸129残基对于新型抑制剂结合的意义
3. Discovery and characterisation of hydrazines as inhibitors of the immune suppressive enzyme, indoleamine 2,3-dioxygenase 1 (IDO1) [J] . FungS.-P.S., WangH., TomekP., Bioorganic and medicinal chemistry . 2013,第24期

机译：发现和表征肼作为免疫抑制酶的抑制剂，吲哚胺2，3-双加氧酶1（IDO1）
4. Important Hydrogen Bond Networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Design Revealed by Crystal Structures of Imidazoleisoindole Derivatives with IDO1 [J] . Peng Yi-Hui, Ueng Shau-Hua, Tseng Chen-Tso, Journal of Medicinal Chemistry . 2016,第1期

机译：咪唑异吲哚衍生物与IDO1的晶体结构揭示了吲哚胺2,3-二加氧酶1（IDO1）抑制剂设计中的重要氢键网络
5. The mouse epididymis: A site of strong andconstitutive expression of the tryptophanmetabolizing enzyme indoleamine2,3-dioxygenase (IDO) [C] . Shigenobu Tone, Aurore Britan, Aicha Jra International Study Group for Tryptophan Research . 2007

机译：小鼠ePIDIDYMIs：一种强硬型肌醇吲哚胺2,3-二恶英酶（IDO）的强硬型表达的部位
6. The Novel Role of Indoleamine 2,3 - Dioxygenase (IDO1) in Supporting Long Lived Antibody Responses [D] . Lightman, Shivana Shalyn Monica Maharaj. 2021

机译：吲哚胺2,3 - 二恶英酶（IDO1）在支持长寿抗体反应中的新作用
7. Effects of Various Phytochemicals on Indoleamine 2,3-Dioxygenase 1 Activity: Galanal Is a Novel, Competitive Inhibitor of the Enzyme [O] . Rie Yamamoto, Yasuko Yamamoto, Shinjiro Imai, 2010

机译：各种植物化学物质对吲哚胺2，3-双加氧酶1活性的影响：加拉纳尔是一种新型的竞争性酶抑制剂。
8. Characterization of the Selective Indoleamine 2,3-Dioxygenase-1 (IDO1) Catalytic Inhibitor EOS200271/PF-06840003 Supports IDO1 as a Critical Resistance Mechanism to PD-(L)1 Blockade Therapy [O] . Bruno Gomes, Gregory Driessens, Derek Bartlett, 2018

机译：选择性吲哚胺的表征2,3-二氧基酶-1（IDO1）催化抑制剂EOS200271 / PF-06840003支持IDO1作为PD-（L）1阻断治疗的临界电阻机制
9. Regulation of T Cell-Mediated Immunity by D Isomers of Inhibitors of Indoleamine-2,3-Dioxygenase. [R] . Munn, D., Mellor, A. 2004

机译：通过吲哚胺-2,3-双加氧酶抑制剂的异构体调节T细胞介导的免疫。

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