Synthesis of aza mono, bi and tricyclic compounds. Evaluation of their anti MDR activity.

Gallo S; Atifi S; Mahamoud A; Santelli Rouvier C; Wolfart K; Molnar J; Barbe J

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Synthesis of aza mono, bi and tricyclic compounds. Evaluation of their anti MDR activity.

机译：氮杂单，双和三环化合物的合成。评估其抗MDR活性。

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摘要

Anti MDR activity of a series of acridine, pyridoquinoline, quinoline and pyridine analogous amines was evaluated. Interesting activity is displayed by tricyclic compounds. Besides ring size, influence of the side chain was studied.

机译：评估了一系列a啶，吡啶并喹啉，喹啉和吡啶类似胺的抗MDR活性。三环化合物显示出令人感兴趣的活性。除了环的大小，还研究了侧链的影响。

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《European Journal of Medicinal Chemistry: Chimie Therapeutique》 |2003年第1期|共8页
作者
Gallo S; Atifi S; Mahamoud A; Santelli Rouvier C; Wolfart K; Molnar J; Barbe J;
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正文语种 eng
中图分类医药、卫生;
关键词
Synthesis; Pulmonary evaluation; Multidrug Resistance Gene; SIZES; Anti M; 多药抗药基因;

机译：Synthesis;Pulmonary evaluation;Multidrug Resistance Gene;SIZES;Anti M;多药抗药基因;

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1. Synthesis of aza mono, bi and tricyclic compounds. Evaluation of their anti MDR activity. [J] . Gallo S, Atifi S, Mahamoud A, European Journal of Medicinal Chemistry: Chimie Therapeutique . 2003,第1期

机译：氮杂单，双和三环化合物的合成。评估其抗MDR活性。
2. Synthesis, anti-inflammatory and analgesic activities evaluation of some mono, bi and tricyclic pyrimidine derivatives. [J] . Sondhi SM, Singh N, Johar M, Bioorganic and Medicinal Chemistry . 2005,第22期

机译：某些单环，双环和三环嘧啶衍生物的合成，抗炎和镇痛活性评估。
3. Synthesis and evaluation of tricyclic dipyrido diazepinone derivatives as inhibitors of secretory phospholipase A2 with anti-inflammatory activity. [J] . Thimmegowda NR, Dharmappa KK, Kumar CS, Current topics in medicinal chemistry . 2007,第8期

机译：三环二吡啶基二氮杂吡啶酮衍生物的合成和评估，该衍生物作为具有抗炎活性的分泌型磷脂酶A2的抑制剂。
4. Synthesis of Sugar-Aza-Crown Ethers and Their Bispyrenyl Derivatives as New Fluorescent Molecular Sensors(Abstracts) [C] . JuanXie, Mickael Menand, Stephane Maisonneuve European Symposium on Organic Chemistry . 2007

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6. Synthesis of Enantioenriched γ-Quaternary Cycloheptenones Using a Combined Allylic Alkylation/Stork–Danheiser Approach: Preparation of Mono- Bi- and Tricyclic Systems [O] . Nathan B. Bennett, Allen Y. Hong, Andrew M. Harned, -1

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7. Acid-Catalyzed Hydrolysis of Bridged Bi- and Tricyclic Compounds. XXVIII. Evaluation of alpha-Values for the Protonation of Norbornenes and Nortricyclanes from Solvent Isotope and Acidity Effects and Their Use to Compare the Characters of the Intermediate Carbocations. [O] . Martti Lajunen, Lennart Kenne, Göran Widmalm, 1991

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Synthesis of aza mono, bi and tricyclic compounds. Evaluation of their anti MDR activity.

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