Functional derivatives of 5-benzo(1, 3)dioxol-5-yl-1-methyl-1H-imidazole-2-carbaldehyde and evaluation of leishmanicidal activity.

Vanelle P; Meuche J; Maldonado J; Crozet MP; Delmas F; Timon David-P

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Functional derivatives of 5-benzo(1, 3)dioxol-5-yl-1-methyl-1H-imidazole-2-carbaldehyde and evaluation of leishmanicidal activity.

机译：5-苯并（1，3）二恶唑-5-基-1-甲基-1H-咪唑-2-甲醛的功能衍生物和杀菌活性的评价。

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摘要

New imidazole derivatives were obtained after subjecting 5-benzo[1, 3]dioxol-5-yl-1-methyl-1H-imidazole-2-carbaldehyde to a Knoevenagel reaction. Some of these compounds exhibit significant in vitro leishmanicidal activity.

机译：使5-苯并[1，3]二恶酚-5-基-1-甲基-1H-咪唑-2-甲醛与Knoevenagel反应后，得到新的咪唑衍生物。这些化合物中的一些表现出显着的体外杀菌作用。

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《European Journal of Medicinal Chemistry: Chimie Therapeutique》 |2000年第1期|共6页
作者
Vanelle P; Meuche J; Maldonado J; Crozet MP; Delmas F; Timon David-P;
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原文格式 PDF
正文语种 eng
中图分类医药、卫生;
关键词
Acrylamides; Imidazoles; Leishmania infantum; 3-(5-benzo(1; 3)dioxol-5-yl-1-methyl-1H imidazol-2-yl)-2-nitroacrylamide; 丙烯酰胺类; 咪唑类; 利什曼原虫; 婴儿;

机译：Acrylamides;Imidazoles;Leishmania infantum;3-(5-benzo(1;3)dioxol-5-yl-1-methyl-1H imidazol-2-yl)-2-nitroacrylamide;丙烯酰胺类;咪唑类;利什曼原虫;婴儿;

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1. Functional derivatives of 5-benzo(1, 3)dioxol-5-yl-1-methyl-1H-imidazole-2-carbaldehyde and evaluation of leishmanicidal activity. [J] . Vanelle P, Meuche J, Maldonado J, European Journal of Medicinal Chemistry: Chimie Therapeutique . 2000,第1期

机译：5-苯并（1，3）二恶唑-5-基-1-甲基-1H-咪唑-2-甲醛的功能衍生物和杀菌活性的评价。
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Functional derivatives of 5-benzo(1, 3)dioxol-5-yl-1-methyl-1H-imidazole-2-carbaldehyde and evaluation of leishmanicidal activity.

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