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Comment on: A meta-analysis of common risk factors associated with the diagnosis of developmental dysplasia of the hip in newborns

机译:评论:与新生儿髋部发育不良相关的常见危险因素的荟萃分析

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With interest we read the review from Ortiz-Neira et al. on risk factors for hip dysplasia in newborns [1 ]. The aim of this study was to assess the magnitude of six predefined risk factors of developmental dysplasia of the hips (DDHs) and to calculate the prevalence rate of DDH. The authors precisely describe the selection criteria for studies to be included in the meta-analysis. However, we have some concerns about their study selection. First, at least two studies included in this meta-analysis report on children in a selected population (with a positive family history, breech presentation or abnormal findings at physical examination), which possibly masks the impact of risk factors [2,3]. Second, the authors have included three case-control studies, which invalidate their calculation of the prevalence of DDH which they have made in the last paragraph of the results [3-5]. This is especially worrisome as the calculation of the study populations in table one did not add up to the denominator mentioned in the results.
机译:我们感兴趣地阅读了Ortiz-Neira等人的评论。新生儿髋关节发育不良的危险因素[1]。这项研究的目的是评估髋部发育不良(DDHs)的六个预定风险因素的大小,并计算DDH的患病率。作者精确地描述了纳入荟萃分析的研究选择标准。但是,我们对他们的研究选择有些担忧。首先,该荟萃分析报告中至少包括两项针对选定人群中的儿童的研究(有积极的家族史,臀位表现或体格检查发现异常),这可能掩盖了危险因素的影响[2,3]。其次,作者纳入了三个病例对照研究,这使他们在结果的最后一段[3-5]中对DDH患病率的计算无效。这尤其令人担忧,因为表一中研究人群的计算未加总结果中提到的分母。

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