Novel immunophenotypic and morphologic presentation in acute myeloid leukemia (AML) with JAK2 V617F mutation.

摘要

To the Editor:JAK2 V617F mutation (V617F), although most commonly seen in chronic myeloproliferative disorder (CMPD), is a rare occurrence in de novo acute myeloid leukemia (AML) (1). It is responsible for excessive myeloid cell proliferation by aberrantly signaling JAK2-asso-ciated receptors.