Controversy on another possible risk of preterm delivery after cervical conization: time interval between conization and conception.

摘要

We have read with the interest the article by Guo et al, "Effects of loop electrosurgical excision procedure or cold knife conization on pregnancy outcomes" [1]. Cold knife conization significantly increased the rate of preterm delivery (PD) of the subsequent pregnancy compared with the control, but loop electrosurgical excision procedure (LEEP) did not. Thus, the risk of PD may depend on the conization procedure. We wish readers to pay attention to another possible risk of after-conization-PD: the time interval between conization and conception.