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Synthesis and characterization of magnetite/hydroxyapatite tubes using natural template for biomedical applications

机译:使用天然模板的生物医学应用磁铁矿/羟基磷灰石管的合成和表征

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摘要

Inorganic nanotubes have attracted much attention during the last few decades for its potential applications in the field of regenerative medicine and controlled drug delivery. In the present work, we have designed and synthesized magnetite hydroxyapatite micro and nanotubes. The first step is the formation of magnetite (Fe3O4) tubes on natural template followed by hydroxyapatite (HAp) bioceramic coated on the Fe3O4 tubes. HAp improves the biocompatibility and stability of the prepared tubes. Sintering at 900 (a similar to) C improves the crystalline stability of nanotubes and removes the natural template. X-ray diffraction, N-2 adsorption-desorption studies (BET), thermogravimetric analysis, differential scanning calorimetry, optical micrographs, field emission scanning electron microscope and transmission electron microscope studies were carried out to confirm the structural and morphological analysis of prepared magnetic tubular structure.
机译:在过去的几十年中,无机纳米管因其在再生医学和受控药物输送领域的潜在应用而引起了人们的广泛关注。在目前的工作中,我们设计并合成了磁铁矿羟基磷灰石微粉和纳米管。第一步是在天然模板上形成磁铁矿(Fe3O4)管,然后在Fe3O4管上涂覆羟基磷灰石(HAp)生物陶瓷。 HAp改善了所制备试管的生物相容性和稳定性。在900℃(与之相似)下烧结提高了纳米管的晶体稳定性,并去除了天然模板。进行了X射线衍射,N-2吸附-脱附研究(BET),热重分析,差示扫描量热法,光学显微照片,场发射扫描电子显微镜和透射电子显微镜研究,以确认所制备的磁性管的结构和形态分析结构体。

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