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首页> 外文期刊>European journal of clinical pharmacology >N-acetyl cysteine in prevention of amphotericin- induced electrolytes imbalances: a randomized, double-blinded, placebo-controlled, clinical trial.
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N-acetyl cysteine in prevention of amphotericin- induced electrolytes imbalances: a randomized, double-blinded, placebo-controlled, clinical trial.

机译:N-乙酰半胱氨酸在预防两性霉素诱导的电解质失衡方面:一项随机,双盲,安慰剂对照的临床试验。

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摘要

Oral n-acetyl cysteine during the amphotericin B treatment course was not significantly effective in preventing or mitigating different features of its nephrotoxicity including decrease of glomerular filtration rate, hypokalemia, hypomagnesemia, and renal potassium as well as magnesium wasting.
机译:在两性霉素B治疗过程中口服n-乙酰半胱氨酸不能有效预防或减轻其肾毒性的不同特征,包括肾小球滤过率降低,低钾血症,低镁血症和肾钾以及镁的浪费。

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