Gum acacia mitigates genetic damage in adenine-induced chronic renal failure in rats

Ali B. H.; Al Balushi K.; Al-Husseini I.; Mandel P.; Nemmar A.; Schupp N.; Ribeiro D. A.

首页> 外文期刊>European journal of clinical investigation >Gum acacia mitigates genetic damage in adenine-induced chronic renal failure in rats

【24h】

Gum acacia mitigates genetic damage in adenine-induced chronic renal failure in rats

机译：阿拉伯树胶减轻了腺嘌呤诱发的慢性肾衰竭大鼠的遗传损伤

获取原文

获取原文并翻译 | 示例

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

团队文献服务 >>

页面导航

摘要
著录项
引文网络
相似文献
相关主题

摘要

Background Subjects with chronic renal failure (CRF) exhibit oxidative genome damage, which may predispose to carcinogenesis, and Gum acacia (GumA) ameliorates this condition in humans and animals. We evaluated here renal DNA damage and urinary excretion of four nucleic acid oxidation adducts namely 8-oxoguanine (8-oxoGua), 8-oxo-7,8-dihydro-20-deoxyguanosine (8-oxodG), 8-oxoguanosine (8-oxoGuo) and 8-hydroxy-2-deoxyguanisone (8-OHdg) in rats with adenine (ADE)-induced CRF with and without GumA treatment.

机译：背景患有慢性肾衰竭（CRF）的受试者表现出氧化基因组损伤，这可能易于致癌，而阿拉伯胶（GumA）可以改善人和动物的这种状况。我们在这里评估了四种DNA氧化加合物的肾脏DNA损伤和尿液排泄物，即8-氧鸟嘌呤（8-oxoGua），8-氧代-7,8-二氢-20-脱氧鸟苷（8-oxodG），8-氧鸟嘌呤（8-腺嘌呤（ADE）诱导的CRF的大鼠在使用和未使用GumA的情况下均对oxoGuo和8-hydroxy-2-deoxyguanisone（8-OHdg）具有影响。

著录项

来源
《European journal of clinical investigation》 |2015年第12期|共7页
作者
Ali B. H.; Al Balushi K.; Al-Husseini I.; Mandel P.; Nemmar A.; Schupp N.; Ribeiro D. A.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类临床医学;
关键词
Adenine; chronic renal failure; Comet test; DNA damage; gum acacia; rats;

机译：腺嘌呤;慢性肾功能衰竭;彗星试验;DNA损伤;阿拉伯树胶;大鼠;

相似文献

外文文献
中文文献
专利

1. Gum acacia mitigates genetic damage in adenine-induced chronic renal failure in rats [J] . Ali B. H., Al Balushi K., Al-Husseini I., European journal of clinical investigation . 2015,第12期

机译：阿拉伯树胶减轻了腺嘌呤诱发的慢性肾衰竭大鼠的遗传损伤
2. Comparative efficacy of three brands of gum acacia on adenine-induced chronic renal failure in rats. [J] . B. H. Ali, S. Beegam, I. Al-Lawati, Physiological Research . 2013,第1期

机译：三种品牌相思树胶对腺嘌呤诱发的大鼠慢性肾功能衰竭的比较功效。
3. New model for adenine-induced chronic renal failure in mice, and the effect of gum acacia treatment thereon: Comparison with rats [J] . AliB.H., Al-SalamS., AlZaabiM., Journal of Pharmacological and Toxicological Methods . 2013,第3期

机译：腺嘌呤诱发的小鼠慢性肾功能衰竭的新模型及其胶合相思治疗的作用：与大鼠的比较
4. Disability Prevention of Chronic Renal Failure (CRF): Beneficial Effects of Combination of Chronic Exercise, and Anti-hypertensive Drugs on Skeletal Capillaries, Exercise Endurance, and Renal Function in Rats with CRF [C] . A. Ishida, M. Kanazawa, H. Lu, International Society of Physical and Rehabilitation Medicine . 2007

机译：残疾预防慢性肾功能衰竭（CRF）：慢性运动结合，抗高血压药物对CRF大鼠骨骼毛细血管，锻炼耐久性和肾功能的益处合
5. Exploiting the use of mesenchymal stromal cells genetically engineered to overexpress insulin-like growth factor-1 in gene therapy of chronic renal failure. [D] . Kucic, Terrence. 2008

机译：利用基因工程的间充质基质细胞在慢性肾衰竭的基因治疗中过表达胰岛素样生长因子-1。
6. Chronic treatment of curcumin improves hepatic lipid metabolism and alleviates the renal damage in adenine-induced chronic kidney disease in Sprague-Dawley rats [O] . Hardik Ghelani, Valentina Razmovski-Naumovski, Dennis Chang, 2019

机译：姜黄素的慢性治疗可改善Sprague-Dawley大鼠在腺嘌呤诱发的慢性肾脏疾病中的肝脂质代谢并减轻肾脏损害
7. Gum Acacia Improves Renal Function and Ameliorates Systemic Inflammation, Oxidative and Nitrosative Stress in Streptozotocin-Induced Diabetes in Rats with Adenine-Induced Chronic Kidney Disease [O] . Mohammed Al Za’abi, Suhail Al Salam, Yousuf Al Suleimani, 2018

机译：牙龈术改善肾功能，并改善腺嘌呤诱导的腺嘌呤致慢性肾病大鼠链脲佐菌素诱导的糖尿病中的全身炎症，氧化和氮化胁迫

Gum acacia mitigates genetic damage in adenine-induced chronic renal failure in rats

摘要

著录项

引文网络

相似文献

相关主题

期刊订阅