Effects of modest hyperoxia and oral vitamin C on exercise hyperaemia and reactive hyperaemia in healthy young men

摘要

We have argued that breathing 40 % O-2 attenuates exercise hyperaemia by decreasing production of O-2-dependent vasodilators. However, breathing 100 % O-2 attenuated endothelium-dependent vasodilatation evoked by acetylcholine and this effect was prevented by vitamin C, implicating reactive oxygen species (ROS). We have therefore used vitamin C to test the hypothesis that 40 % O-2 modulates exercise hyperaemia and reactive hyperaemia independently of ROS.