Can Campylobacter coli induce Guillain-Barre syndrome?

摘要

Campylobacter jejuni enteritis is the most frequently identified infection preceding the Guillain-Barre syndrome (GBS) and neural damage is thought to be induced through molecular mimicry between C. jejuni lipo-oligosaccharide (LOS) and human gangliosides [1]. It has been questioned whether or not other Campylobacter species, including C. curvus, C. upsaliensis and C: coli, could be similarly involved [2-4]. This is relevant because it would imply that bacterial factors considered important in the aetiology of GBS crossed species barriers. Two prior reports have appeared where C. coli was putatively associated with a case of GBS [2,3].