Fatal outcome during anaesthesia induction in a patient with amiodarone-induced thyrotoxicosis.

摘要

Amiodarone is a class III anti-arrhythmic drug which has been used in Europe since 1967 to treat angina and refractory arrhythmias of supraven-tric'ular, junctional and ventricular origin . It is an iodinated benzofuran derivative with a molecular structure that is similar to thyroxine and tri-iodothyronine . It has a high iodine content (37% per weight). A significant amount of iodine is liberated during drug metabolism .