Topography of primitive reflexes in dementia: an F-18 fluorodeoxyglucose positron emission tomography study

摘要

Background and purposeAlthough primitive reflexes (PRs) are inhibited during the first years of childhood, they may reappear with brain injury. PRs have been linked to frontal lobe dysfunction, but their precise topography has not yet been defined. The purpose of this study was to map which regions of the brain display a reduced glucose metabolism in patients with cognitive impairment and PRs.