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Highlights lecture EANM 2015: the search for nuclear medicine's superheroes

机译:2015年EANM演讲重点:寻找核医学的超级英雄

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The EANM 2015 Annual Congress, held from October 10th to 14th in Hamburg, Germany, was outstanding in many respects. With 5550 participants, this was by far the largest European congress concerning nuclear medicine. More than 1750 scientific presentations were submitted, with more than 250 abstracts from young scientists, indicating that the future success of our discipline is fuelled by a high number of young individuals becoming involved in a multitude of scientific activities. Significant improvements have been made in molecular imaging of cancer, particularly in prostate cancer. PSMA-directed PET/CT appears to become a new gold standard for staging and restaging purposes. Novel tumour specific compounds have shown their potential for target identification also in other solid neoplasms and further our understanding of tumour biology and heterogeneity. In addition, a variety of nuclear imaging techniques guiding surgical interventions have been introduced. A particular focus of the congress was put on targeted, radionuclide based therapies. Novel theranostic concepts addressing also tumour entities with high incidence rates such as prostate cancer, melanoma, and lymphoma, have shown effective anti-tumour activity. Strategies have been presented to improve further already established therapeutic regimens such as somatostatin receptor based radio receptor therapy for treating advanced neuroendocrine tumours. Significant contributions were presented also in the neurosciences track. An increasing number of target structures of high interest in neurology and psychiatry are now available for PET and SPECT imaging, facilitating specific imaging of different subtypes of dementia and movement disorders as well as neuroinflammation. Major contributions in the cardiovascular track focused on further optimization of cardiac perfusion imaging by reducing radiation exposure, reducing scanning time, and improving motion correction. Besides coronary artery disease, many contributions focused on cardiac inflammation, cardiac sarcoidosis, and specific imaging of large vessel vasculitis. The physics and instrumentation track included many highlights such as novel, high resolution scanners. The most noteworthy news and developments of this meeting were summarized in the highlights lecture. Only 55 scientific contributions were mentioned, and hence they represent only a brief summary, which is outlined in this article. For a more detailed view, all presentations can be accessed by the online version of the European Journal of Nuclear Medicine and Molecular Imaging (Volume 42, Supplement 1).
机译:10月10日至14日在德国汉堡举行的EANM 2015年会在许多方面都非常出色。有5550名与会者,这是迄今为止欧洲最大的核医学大会。提交了1750多份科学报告,其中有250多份来自年轻科学家的摘要,这表明我们学科的未来成功是由大量参与各种科学活动的年轻人推动的。在癌症的分子成像中,尤其是在前列腺癌中,已经取得了显着的进步。 PSMA导向的PET / CT似乎已成为分期和重新分期的新金标准。新型肿瘤特异性化合物还显示出了其在其他实体瘤中进行靶标鉴定的潜力,进一步加深了我们对肿瘤生物学和异质性的理解。另外,已经引入了指导手术干预的多种核成像技术。大会的特别重点是针对性的,基于放射性核素的疗法。还解决了诸如前列腺癌,黑色素瘤和淋巴瘤等高发病率的肿瘤实体的新型治疗论概念已经显示出有效的抗肿瘤活性。已经提出了改善进一步建立的治疗方案的策略,例如基于生长抑素受体的放射受体疗法,用于治疗晚期神经内分泌肿瘤。在神经科学领域也有重要贡献。现在,越来越多的对神经病学和精神病学感兴趣的靶结构可用于PET和SPECT成像,从而促进了痴呆和运动障碍以及神经炎症的不同亚型的特异性成像。心血管领域的主要贡献在于通过减少辐射暴露,减少扫描时间和改善运动校正来进一步优化心脏灌注成像。除冠状动脉疾病外,许多贡献还集中在心脏炎症,心脏结节病和大血管血管炎的特殊成像方面。物理和仪器领域包括许多亮点,例如新颖的高分辨率扫描仪。重点演讲总结了这次会议最值得注意的新闻和进展。仅提及了55项科学贡献,因此,它们仅代表本文的概述。要获得更详细的视图,可以通过《欧洲核医学和分子影像学杂志》的在线版本(第42卷,补编1)访问所有演示文稿。

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