High- and low-dose-rate intraoperative radiotherapy for thoracic malignancies resected with close or positive margins

摘要

PURPOSE: Local recurrence is a significant problem after surgical resection of thoracic tumors. As intraoperative radiotherapy (TORT) can deliver radiation directly to the threatened margin, we have used this therapy in an attempt to reduce local recurrence, using high-dose-rate (HDR) as well as low-dose-rate (LDR) techniques.