Autonomic changes following generalized tonic clonic seizures: An analysis of adult and pediatric patients with epilepsy

Sarkis Rani A.; Thome-Souza Sigride; Poh Ming-Zher; Llewellyn Nichelle; Klehm Jacquelyn; Madsen Joseph R.; Picard Rosalind; Pennell Page B.; Dworetzky Barbara A.; Loddenkemper Tobias; Reinsberger Claus

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Autonomic changes following generalized tonic clonic seizures: An analysis of adult and pediatric patients with epilepsy

机译：全身性强直性阵挛性癫痫发作后的自主神经改变：成人和小儿癫痫患者的分析

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Objective: Sudden unexpected death in epilepsy (SUDEP) is the most common cause of mortality directly related to epilepsy. Its incidence is higher in adult patients and its pathophysiology remains poorly understood, but likely involves autonomic dysregulation following generalized tonic clonic seizures (GTCS). In the current study, we aimed to analyze post-ictal autonomic changes following GTCS in adult and pediatric patients.

机译：目的：癫痫猝死（SUDEP）是与癫痫直接相关的最常见死亡原因。它的发病率在成年患者中较高，并且对其病理生理学仍然知之甚少，但可能涉及全身性强直性阵挛性癫痫发作（GTCS）后的自主神经调节异常。在当前的研究中，我们旨在分析成年和小儿患者GTCS后发作后自主神经的变化。

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《Epilepsy research》 |2015年第null期|共6页
作者
Sarkis Rani A.; Thome-Souza Sigride; Poh Ming-Zher; Llewellyn Nichelle; Klehm Jacquelyn; Madsen Joseph R.; Picard Rosalind; Pennell Page B.; Dworetzky Barbara A.; Loddenkemper Tobias; Reinsberger Claus;
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正文语种 eng
中图分类神经病学;
关键词
Generalized tonic clonic seizures; Sudden unexpected death in epilepsy; Autonomic nervous system; Electrodermal activity; Post-ictal generalized EEG suppression;

机译：全身性强直性阵挛性癫痫发作;癫痫猝死;自主神经系统;皮肤活动;发作后全身性脑电图抑制;

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1. Autonomic changes following generalized tonic clonic seizures: An analysis of adult and pediatric patients with epilepsy [J] . Sarkis Rani A., Thome-Souza Sigride, Poh Ming-Zher, Epilepsy research . 2015,第Null期

机译：全身性强直性阵挛性癫痫发作后的自主神经改变：成人和小儿癫痫患者的分析
2. SCN1A mutation analysis in myoclonic astatic epilepsy and severe idiopathic generalized epilepsy of infancy with generalized tonic-clonic seizures. [J] . Ebach K, Joos H, Doose H, Neuropediatrics . 2005,第3期

机译：SCN1A突变分析在肌阵挛性静止性癫痫和重度特发性阵挛性发作的婴儿的严重特发性全身性癫痫中。
3. Pregabalin as adjunctive therapy in adult and pediatric patients with generalized tonic-clonic seizures: A randomized, placebo-controlled trial [J] . Joseph Driscoll, Mary Almas, Gabriela Gregorian, Epilepsia Open . 2021,第2期

机译：普瑞巴林作为成人和小儿助药症患者的辅助治疗：随机，安慰剂对照试验
4. Online detection of tonic-clonic seizures in pediatric patients using ECG and low-complexity incremental novelty detection [C] . De Cooman Thomas, Van de Vel Anouk, Ceulemans Berten, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2015

机译：使用ECG和低复杂度增量新颖性检测技术在线检测小儿强直阵挛性癫痫
5. Ventral Pallidum Deep Brain Stimulation Has Potent Efficacy for Generalized Tonic-Clonic Seizures in the Pentylenetetrazole Rat Model of Epilepsy [D] . Zeng, Andrew J. 2020

机译：腹侧Pallidum深脑刺激对癫痫戊酮大鼠大鼠模型中的普通滋补克隆癫痫发作具有有效的疗效
6. Multimodal Data and Machine Learning for Detecting Specific Biomarkers in Pediatric Epilepsy Patients With Generalized Tonic-Clonic Seizures [O] . Jianping Wang, Yongxin Li, Ya Wang, 2018

机译：多模式数据和机器学习用于检测小儿癫痫患者广泛性强直阵挛性癫痫发作的特定生物标志物
7. SCN1A mutation analysis in Myoclonic Astatic Epilepsy and Severe Idiopathic Generalized Epilepsy of Infancy with Generalized Tonic Clonic Seizures [O] . Ebach Katharina 2005

机译：肌阵挛性静止性癫痫和重度特发性婴儿广泛性阵挛性阵挛性癫痫的SCN1A突变分析

Autonomic changes following generalized tonic clonic seizures: An analysis of adult and pediatric patients with epilepsy

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