In vitro transport assays of rufinamide, pregabalin, and zonisamide by human P-glycoprotein.

Pui Shan Chan; Chunbo Zhang; Zhong Zuo; Patrick Kwan; Larry Baum

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In vitro transport assays of rufinamide, pregabalin, and zonisamide by human P-glycoprotein.

机译：人P糖蛋白对芦丁酰胺，普瑞巴林和唑尼沙胺的体外转运测定。

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ZNS, RFM, and PGB are not substrates of human Pgp. These data suggest that resistance to these drugs may not be attributed to increased Pgp activity in resistant patients.

机译：ZNS，RFM和PGB不是人类Pgp的底物。这些数据表明，对这些药物的抗药性可能不归因于抗药性患者中Pgp活性的提高。

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《Epilepsy research》 |2014年第3期|共8页
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Pui Shan Chan; Chunbo Zhang; Zhong Zuo; Patrick Kwan; Larry Baum;
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1. In vitro transport assays of rufinamide, pregabalin, and zonisamide by human P-glycoprotein. [J] . Pui Shan Chan, Chunbo Zhang, Zhong Zuo, Epilepsy research . 2014,第3期

机译：人P糖蛋白对芦丁酰胺，普瑞巴林和唑尼沙胺的体外转运测定。
2. In vitro concentration dependent transport of phenytoin and phenobarbital, but not ethosuximide, by human P-glycoprotein. [J] . Zhang C, Kwan P, Zuo Z, Life sciences . 2010,第23a24期

机译：人P-糖蛋白的体外浓度依赖于苯妥英和苯巴比妥的转运，而不是依托昔布胺的转运。
3. Proposal for fluorescence-based in vitro assay using human and zebrafish monoamine transporters to detect biological activities of antidepressants in wastewater [J] . Masaru Ihara, Han Zhang, Mariko O. Ihara, Science of the total environment . 2021,第MAYa20期

机译：使用人和斑马鱼单胺转运蛋白基于荧光的体外测定的提议检测废水中抗抑郁药的生物学活性
4. Development of a Gabapentin/Pregabalin (GP) Assay Using a High-Throughput RapidFire-MS/MS System [C] . Jennifer C. Hitchcock, Jeffrey R. Enders, Ayodele A. Morris, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2013

机译：使用高通量RapidFire-MS / MS系统进行加布邦/普瑞巴林（GP）测定的研制
5. Dietary effects on drug metabolism and transport: Effect of peppermint oil, St. John's Wort, and fruit juices on cytochrome P450 3A4, P-glycoprotein, and organic anion transporting polypeptides in vitro and in humans [D] . Dresser, George K. 2004

机译：饮食对药物代谢和转运的影响：薄荷油，圣约翰草和果汁对体外和人体中细胞色素P450 3A4，P-糖蛋白和有机阴离子转运多肽的影响
6. Transport of celiprolol across human intestinal epithelial (Caco-2) cells: mediation of secretion by multiple transporters including P-glycoprotein. [O] . J. Karlsson, S. M. Kuo, J. Ziemniak, 1993

机译：头孢洛尔跨人肠道上皮（Caco-2）细胞的运输：包括P糖蛋白在内的多种转运蛋白对分泌的介导。
7. Transport of celiprolol across human intestinal epithelial (Caco-2) cells: mediation of secretion by multiple transporters including P-glycoprotein. [O] . Karlsson, J., Kuo, S. M., Ziemniak, J., 1993

机译：头孢洛尔跨人肠道上皮（Caco-2）细胞的运输：包括P糖蛋白在内的多种转运蛋白对分泌的介导。

In vitro transport assays of rufinamide, pregabalin, and zonisamide by human P-glycoprotein.

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