Lacosamide tolerability in adult patients with partial-onset seizures: Impact of planned reduction and mechanism of action of concomitant antiepileptic drugs

Foldvary-Schaefer Nancy; Fong Joanna S.; Morrison Shannon; Wang Lu; Bena James

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Lacosamide tolerability in adult patients with partial-onset seizures: Impact of planned reduction and mechanism of action of concomitant antiepileptic drugs

机译：成年部分发作性癫痫患者对拉考酰胺的耐受性：计划降低的剂量和同时使用的抗癫痫药的作用机制

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Objective: We evaluated the impact of planned dose reduction and mechanism of action of concomitant AEDs on tolerability in adults with partial-onset seizures undergoing lacosamide (LCM) titration.

机译：目的：我们评估了计划剂量降低和伴随AED作用对接受拉可酰胺（LCM）滴定的部分发作的成年人的耐受性的影响。

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来源
《Epilepsy & behavior: E&B》 |2016年第1期|共6页
作者
Foldvary-Schaefer Nancy; Fong Joanna S.; Morrison Shannon; Wang Lu; Bena James;
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原文格式 PDF
正文语种 eng
中图分类脑部疾病;
关键词
Lacosamide; Tolerability; Mechanism of action; Standardized dose;

机译：拉考酰胺;耐受性;作用机理;标准剂量;

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1. Lacosamide tolerability in adult patients with partial-onset seizures: Impact of planned reduction and mechanism of action of concomitant antiepileptic drugs [J] . Foldvary-Schaefer Nancy, Fong Joanna S., Morrison Shannon, Epilepsy & behavior: E&B . 2016,第Pta1期

机译：成年部分发作性癫痫患者对拉考酰胺的耐受性：计划降低的剂量和同时使用的抗癫痫药的作用机制
2. Safety and tolerability of adjunctive lacosamide intravenous loading dose in lacosamide-naive patients with partial-onset seizures [J] . FountainN.B., KraussG., IsojarviJ., Epilepsia: Journal of the International League against Epilepsy . 2013,第1期

机译：初次服用Lacosamide的部分发作性癫痫患者的辅助Lacosamide静脉内负荷剂量的安全性和耐受性
3. Impact of perampanel on pharmacokinetics of concomitant antiepileptics in patients with partial-onset seizures: pooled analysis of clinical trials [J] . Majid Oneeb, Laurenza Antonio, Ferry Jim, British Journal of Clinical Pharmacology . 2016,第2期

机译：Perampanel对部分发作性癫痫患者并发抗癫痫药药代动力学的影响：临床试验汇总分析
4. Mining Patients' Reviews in Online Health Communities for Adverse Drug Reaction Detection of Antiepileptic Drugs [C] . Anwar Ali Yahya, Yousef Asiri, Ibrahim Alyami International Arab Conference on Information Technology . 2020

机译：在线卫生社区中的矿产患者评论因抗癫痫药物的不良药物反应检测
5. THE MECHANISM OF ACTION OF ANTIEPILEPTIC DRUG: THE EFFECT OF THE DRUGS ON L-GLUTAMIC ACID DECARBOXYLASE RETARDED BY THIOSEMICARBAZIDE. [D] . HIRANO, KANEO. 1963

机译：抗菌药物的作用机理：药物对硫代咪唑叠氮阻滞的L-葡萄糖酸脱羧酶的影响。
6. Interactions among Lacosamide and Second-Generation Antiepileptic Drugs in the Tonic-Clonic Seizure Model in Mice [O] . Katarzyna Załuska-Ogryzek, Paweł Marzęda, Paula Wróblewska-Łuczka, 2021

机译：小鼠滋补克隆癫痫发作模型中涂层酰胺和第二代抗癫痫药物的相互作用
7. Safety and tolerability of adjunctive lacosamide intravenous loading dose in lacosamide-naive patients with partial-onset seizures [O] . Nathan B. Fountain, Gregory Krauss, Jouko Isojarvi, 2012

机译：延迟瘤瘤鼻腔内脉络患者静脉酰胺静脉注射剂量的安全性和耐受性

Lacosamide tolerability in adult patients with partial-onset seizures: Impact of planned reduction and mechanism of action of concomitant antiepileptic drugs

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