Commentary on the 1st International Summer School for Neuropathology and Epilepsy Surgery (INES 2013) held in Erlangen, Germany, September 16-20, 2013

摘要

Epilepsy surgery is increasingly available as a successful treatment option in patients with drug-resistant focal epilepsies when associated with distinct brain lesions. Reliable neuropathologic work-up of epilepsy-associated brain lesions represents, therefore, an important diagnostic tool in clinical epileptology, and the International League Against Epilepsys international classification of epilepsies recognizes a large spectrum of neuropathologic substrates as potential predictors of each patients disease progression and treatment response. However, histopatho-logic standards are not yet available for all different lesions encountered in patients with epilepsy, nor are they very well accepted or disseminated among the diagnostic pathology community. In addition, the microscopic diagnosis of epilepsy-related surgical brain specimens remains challenging due to the broad spectrum of disease variants.