Uterine fibroids (leiomyomata) are the most common pelvic tumors in U.S. women as well as the most common cause for hysterectomy. Both estrogen and progesterone influence fibroid development, whereas early-life hormonal exposures can affect uterine development and a woman's response to estrogen or progesterone later in life. In a new study, researchers investigate novel hypotheses regarding fibroid pathogenesis in relation to early-life exposures, most of which have not been explored previously
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