Effect of testosterone on the immune response of the Indian major carp Labeo rohita (Ham.) to Aeromonas hydrophila vaccine.

摘要

The dose dependent effect of testosterone on specific immune response and protective immunity of Labeo rohita was studied. The specific immune response was studied by antibody agglutination test while protective immunity was tested by challenging the fish with potent strain of bacterial fish pathogen, Aeromonas hydrophila. The low dose of testosterone (5 ppm) enhanced the humoral immunity while the dose (25 ppm) was dose (25 ppm) was found to suppress it. It was also observed that the high dose of testosterone decreased the protective immunity against the pathogen and the low dose had no adverse effect on protective immunity.