Combination of temsirolimus and adriamycin exhibits an enhanced antitumor effect in hepatocellular carcinoma

Kang Hong-Gang; Wang Bao-Zhong; Zhang JingLiu Mei-RongLi Ying-Xue

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Combination of temsirolimus and adriamycin exhibits an enhanced antitumor effect in hepatocellular carcinoma

机译：替西罗莫司和阿霉素联合使用在肝细胞癌中表现出增强的抗肿瘤作用

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Objective: The oncogenic PI3K/ Akt/mTOR pathway is frequently activated in hepatocellular carcinoma (HCC). The aim of this study is to investigate the anti-HCC effect of combination of temsirolimus, an mTOR inhibitor, and adriamycin, a routinely used drug for treating HCC.

机译：目的：致癌PI3K/Akt/mTOR通路在肝细胞癌（HCC）中经常被激活。本研究的目的是研究替西罗莫司（一种 mTOR 抑制剂）和阿霉素（一种治疗 HCC 的常规药物）联合使用的抗 HCC 作用。

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《Clinics and research in hepatology and gastroenterology 》 |2017年第2期| 197-203| 共7页
作者
Kang Hong-Gang; Wang Bao-Zhong; Zhang JingLiu Mei-RongLi Ying-Xue;
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作者单位

Liaocheng Peoples Hosp, Dept Oncol, 67 Dongchang West Rd, Liaocheng, Shandong, Peoples R China;

Liaocheng Peoples Hosp, Dept Pathol, Liaocheng, Peoples R China;

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正文语种英语
中图分类消化系及腹部疾病 ;
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Combination of temsirolimus and adriamycin exhibits an enhanced antitumor effect in hepatocellular carcinoma

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