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ECONOMIC IMPACT OF NEW FORMS OF ANTIMICROBIAL TREATMENT FOR NOSOCOMIAL PNEUMONIA IN CARDIOVASCULAR INTENSIVE CARE UNITS

机译:心血管重症监护病房院内肺炎新型抗菌治疗的经济影响

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摘要

Nosocomial pneumonia (NP) are those that appear 48 hours after hospital admission, and they are the sec-ond leading cause of infection in general wards and the first cause in intensive care units (ICUs) worldwide. Its incidence has been reported between 10-20, which can reach up to 20 in patients receiving artifi-cial mechanical ventilation, and its mortality exceeds 501-3; that is why they are considered diseases of high morbidity, mortality and socio-economic impact.Early empirical treatment with broad-spectrum an-timicrobial is the correct first step in order to reduce its mortality; however, this therapeutic potential may expose the patient to overdose of antibiotics, so de-escalation of these drugs is a strategy to replace them with a simple but effective therapy, after knowing the results of microbiological cultures and having a satis-factory clinical course4-8.
机译:院内肺炎 (NP) 是指入院后 48 小时出现的肺炎,是普通病房感染的第二大病因,也是全球重症监护病房 (ICU) 的首要病因。据报道,其发病率在10-20%之间,在接受人工机械通气的患者中可高达20%,死亡率超过50%1-3;这就是为什么它们被认为是高发病率、死亡率和社会经济影响的疾病。早期经验性治疗广谱抗微生物药物是降低其死亡率的正确第一步;然而,这种治疗潜力可能会使患者暴露于过量的抗生素,因此在了解微生物培养结果并具有令人满意的临床疗程后,用简单但有效的疗法来降低这些药物的降级是一种策略4-8。

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