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机译:视觉小插图

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Case Presentation: A 59-year-old previously healthy man presented with 6 months of progressive vision loss, which was greater in the left than right eye and had become worse over the 2 weeks prior to presentation. He denied focal weakness, slurred speech, seizures, or headaches. On exam, he was alert and oriented with no focal weakness but had bilateral inferior-temporal visual field defects and pale optic nerves. Brain magnetic resonance imaging (MRI) revealed a suprasellar heterogeneous mass (5.3 x 2.7 x 2.5 cm) with solid and fluid components and displacement of the optic chiasm. The pituitary gland appeared normal (Fig. 1). Laboratory panel revealed a free thyroxine level of 0.8 ng/dL (normal, 0.5 to 1.6 ng/dL), thyroid-stimulating hormone level of 0.65 mlU/L (normal, 0.34 to 5.6 mlU/L), testosterone level of 250 ng/dL (normal, 270 to 1,100 ng/dL), follicle-stimulating hormone level of 6 IU/L (normal, 1 to 8 IU/L), luteinizing hormone level of 4 IU/L (normal, 2 to 12 IU/L), prolactin level of 2 ng/mL (normal, 2 to 19 ng/mL), insulin-like growth factor-1 level of 164 ng/dL (normal, 56 to 271 ng/dL), and a morning cortisol level of <0.4 mug/dL (normal, 6.7 to 22.6 mug/dL). The patient was on intravenous dexamethasone (4 mg) every 6 hours. Additional preoperative studies included computed tomography (CT) angiogram and cerebral angiogram (Fig. 2). What is the diagnosis?
机译:病例报告:一位59岁以前健康的人出现了6个月的渐进视力丧失,左眼比右眼更大,并且在陈述前2周变得更糟。他否认病灶无力,言语含糊,癫痫发作或头痛。在检查中,他机敏,定向,无局灶性弱点,但有双侧颞下视野缺损和视神经苍白。脑磁共振成像(MRI)显示了上层异质性肿块(5.3 x 2.7 x 2.5 cm),具有固体和液体成分以及视交叉的移位。垂体呈正常状态(图1)。实验室小组发现游离甲状腺素水平为0.8 ng / dL(正常,为0.5至1.6 ng / dL),促甲状腺激素水平为0.65 mlU / L(正常,为0.34至5.6 mlU / L),睾丸激素水平为250 ng / d dL(正常,270至1,100 ng / dL),促卵泡激素水平为6 IU / L(正常,1至8 IU / L),黄体激素水平为4 IU / L(正常,2至12 IU / L) ),催乳素水平为2 ng / mL(正常2至19 ng / mL),胰岛素样生长因子-1水平为164 ng / dL(正常56至271 ng / dL),早晨皮质醇水平为<0.4杯/分升(正常,6.7至22.6杯/分升)。该患者每6小时接受一次静脉地塞米松(4 mg)。术前的其他研究包括计算机断层扫描(CT)血管造影和脑血管造影(图2)。诊断是什么?

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