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首页> 外文期刊>Endocrine practice: official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists >ADULT HYPOPHOSPHATASIA TREATED WITH TERIPARATIDE: REPORT OF 2 PATIENTS AND REVIEW OF THE LITERATURE
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ADULT HYPOPHOSPHATASIA TREATED WITH TERIPARATIDE: REPORT OF 2 PATIENTS AND REVIEW OF THE LITERATURE

机译:特立哌肽治疗成人低眼球症:2例患者的报告并文献复习

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摘要

Objective: Hypophosphatasia (HPP) is a rare inherited metabolic bone disease from deficient activity of the tissue-nonspecific isoenzyme of alkaline phosphatase (TNSALP). Reportedly, teriparatide (parathyroid hormone 1-34) can benefit the adult form of HPP, including fracture healing. We studied 2 women with adult HPP given teriparatide and reviewed the reports of 6 additional patients.
机译:目的:低磷血症(HPP)是一种罕见的遗传性骨代谢疾病,由于碱性磷酸酶的组织非特异性同工酶(TNSALP)活性不足。据报道,特立帕肽(甲状旁腺激素1-34)可以使成人HPP受益,包括骨折愈合。我们研究了两名接受特立帕肽治疗的成年HPP妇女,并复查了另外6例患者的报告。

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