Images in endocrine pathology: A starry-sky in the thyroid

摘要

A 72-year-old Caucasian woman, with fever for 2 weeks, presented to our thyroid center for investigation of a 3-cm nodule in the left thyroid lobe that was discovered by her family doctor. Thyroid ultrasound (US) revealed a hypoechoic solid nodule with ill-defined borders. A US-guided fine needle-aspiration (FNA) was performed (Fig. 1a, b) and a cell block was prepared for ancillary studies (Fig. 1c), followed by ~(18)F-fluofodeoxyglucose positron emission tomography/computed tomography (~(18)FDG PET/CT) (Fig. 1d), thyroid biopsy (Fig. 1e), and fluorescent in situ hybridization (FISH) analysis (Fig. If).