Effects of 1-deamino-1-monocarb-arginine-vasotocin on sodium ion and water excretion by rat kidneys.

摘要

Injection of 1-deamino-1-monocarb-arginine-vasotocin (0.05 microg/100 g body weight) to alert rats caused increased natriuresis, diuresis, and reabsorption of osmotically free water. Injection of furosemide (0.5 mg/100 g body weight) increased Na(+) excretion and did not increase reabsorption of osmotically free water. 1-deamino-1-monocarb-arginine-vasotocin in molar conversion increased natriuresis by almost 6 x 10(4) times more effectively than furosemide.