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New Design forDetection Cell Applied in Magnetic Particle-Based Electrochemiluminescence Assays

机译:检测池的新设计在基于磁性粒子的电化学发光测定中的应用

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摘要

A new configuration of detection cell has been designed for convenient magnetic particles (MPs)-based electrochemiluminescence (ECL) assays preformed on the instruments in which the photomultiplier tube is under the working electrode (WE) side. The design provides easy physical cleaning of WE and avoids impurity precipitates depositing on the electrode surface. Subsequently, effects of different MPs without and with graphene (named CMNs and GHPMNs, respectively) on ECL efficiency were compared for the first time. CMNs would decrease the ECL due to the low conductivity of Fe3O4 itself. Because of the intrinsic high conductivity of graphene, GHPMNs could lead to 6–7-fold increase in ECL intensity.
机译:设计了一种新的检测单元配置,以方便在光电倍增管位于工作电极(WE)侧下方的仪器上进行的基于磁性粒子(MPs)的电化学发光(ECL)分析。该设计可轻松对WE进行物理清洁,并避免杂质沉淀物沉积在电极表面。随后,首次比较了不使用石墨烯和使用石墨烯的不同MP(分别称为CMN和GHPMN)对ECL效率的影响。由于Fe3O4本身的低电导率,CMNs会降低ECL。由于石墨烯固有的高电导率,因此GHPMNs可能导致ECL强度增加6-7倍。

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