Gold and Nanogold Electrodes Modified with Gold Nanoparticles and meso-2,3-Dimercaptosuccinic Acid for the Simultaneous, Sensitive and Selective Determination of Dopamine and Its Biogenic Interferents

摘要

Gold and nanogold electrodes modified with self-assembled layers composed of gold nanoparticles and organic sulfur compounds were applied for quantitative determination of dopamine and its biogenic interferents like: ascorbic and uric acids. For the novel sensor a linear relationship between the current response of dopamine at the potential of peak maximum and the concentration was found over a wide analyte concentration range in solution with a very good detection sensitivity and detection limit. It was proved that current peaks of dopamine and both ascorbic and uric acids were clearly separated from each other enabling selective detection of these compounds coexisting in a mixture in solution of pH 7.