Time Course of Histone Deacetylase 1 and Acetylated H3 and H4 Histones in the Brain of Rats Treated with Ladasten

M. Kh. Salimgareeva; S. V. Sadovnikov; R. S. Yamidanov; Yu. V. Vakhitova; S. B. Seredenin

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Time Course of Histone Deacetylase 1 and Acetylated H3 and H4 Histones in the Brain of Rats Treated with Ladasten

机译：拉达斯坦治疗的大鼠脑中组蛋白脱乙酰基酶1和乙酰化的H3和H4组蛋白的时程

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We studied the effects of single intragastric administration of ladasten in a dose of 50 mg/kg on the time course of histone deacetylase 1 (HDAC1) and levels of acetylated histones H3 (Lys9) and H4 (Lys8) in the striatum, hippocampus, and hypothalamus. Ladasten reduced HDAC1 level in rat striatum and hippocampus and modified H3acK9 and H4acK8 levels in various structures of rat brain.

机译：我们研究了单次胃内给予拉达斯汀50 mg / kg对组蛋白脱乙酰基酶1（HDAC1）的时间进程以及纹状体，海马体中乙酰化组蛋白H3（Lys9）和H4（Lys8）水平的影响。下丘脑。 Ladasten降低了大鼠纹状体和海马中的HDAC1水平，并修饰了大鼠大脑各种结构中的H3acK9和H4acK8水平。

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《Bulletin of experimental biology and medicine 》 |2011年第5期| 共4页
作者
M. Kh. Salimgareeva; S. V. Sadovnikov; R. S. Yamidanov; Yu. V. Vakhitova; S. B. Seredenin;
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正文语种 eng
中图分类基础医学 ;
关键词
acetylated histones; histone deacylases; chromatin; HDAC inhibitors; neuro-protection;

机译：乙酰化组蛋白;组蛋白脱酰基;染色质;HDAC抑制剂;神经保护;

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1. Time Course of Histone Deacetylase 1 and Acetylated H3 and H4 Histones in the Brain of Rats Treated with Ladasten [J] . M. Kh. Salimgareeva, S. V. Sadovnikov, R. S. Yamidanov, Bulletin of experimental biology and medicine . 2011 ,第5期

机译：拉达斯坦治疗的大鼠脑中组蛋白脱乙酰基酶1和乙酰化的H3和H4组蛋白的时程
2. Variations in DNA methylation, acetylated histone H4, and methylated histone H3 during Pinus radiata needle maturation in relation to the loss of in vitro organogenic capability [J] . Valledor Luis, Meijon Monica, Hasbun Rodrigo, Journal of Plant Physiology . 2010 ,第5期

机译：辐射松针成熟过程中DNA甲基化，乙酰化组蛋白H4和甲基化组蛋白H3的变化与体外器官发生能力的丧失有关
3. The expression patterns and correlations of claudin-6, methy-CpG binding protein 2, DNA methyltransferase 1, histone deacetylase 1, acetyl-histone H3 and acetyl-histone H4 and their clinicopathological significance in breast invasive ductal carcinomas [J] . Xiaoming Xu, Huiying Jin, Yafang Liu, Diagnostic pathology . 2012 ,第4期

机译：乳腺浸润性导管癌中claudin-6，Methy-CpG结合蛋白2，DNA甲基转移酶1，组蛋白脱乙酰基酶1，乙酰组蛋白H3和乙酰组蛋白H4的表达模式，相关性及其临床病理意义
4. Targeted Quantitative Analysis of Acetylated Histone H4 sites K5, K8, K12, K16 [C] . Marc Gentzel, Asifa Akhtar American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2009

机译：乙酰组蛋白H4位点K5，K8，K12，K16的靶向定量分析
5. Investigation of Parameters of Chromatin Higher Order Structure and the Making of Multiply-Acetylated Histone H3 via Nonsense Suppression [D] . Young, Isaac A. 2021

机译：染色质高阶结构参数的研究及乘法抑制作用乘法致乙酰化组蛋白H3
6. Peptide Mass Mapping of Acetylated Isoforms of Histone H4 from Mouse Lymphosarcoma Cells Treated with Histone Deacetylase (HDACs) Inhibitors [O] . Chen Ren, Liwen Zhang, Michael A. Freitas, -1

机译：组蛋白去乙酰化酶（HDACs）抑制剂治疗小鼠淋巴肉瘤细胞中组蛋白H4的乙酰化同工型的肽质量图
7. Study of in vitro phosphorylation of histones H3, H4 and of the non-acetylated and acetylated tetramers (H3–H4)2 [O] . Martinage A., Mangeat P., Sautiere P., 1981

机译：组蛋白H3，H4以及未乙酰化和乙酰化的四聚体（H3-H4）2的体外磷酸化研究

Time Course of Histone Deacetylase 1 and Acetylated H3 and H4 Histones in the Brain of Rats Treated with Ladasten

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