首页> 外文期刊>Bulletin of experimental biology and medicine >Effect of Annexin V on Development of Apoptosis in Placental Syncytiotrophoblast Nuclei during Exacerbation of Cytomegalovirus Infection in the Third Trimester
【24h】

Effect of Annexin V on Development of Apoptosis in Placental Syncytiotrophoblast Nuclei during Exacerbation of Cytomegalovirus Infection in the Third Trimester

机译:膜联蛋白V对妊娠晚期巨细胞病毒感染加重期间胎盘合体滋养细胞核细胞凋亡发展的影响

获取原文
获取原文并翻译 | 示例
获取外文期刊封面目录资料

摘要

During exacerbation of cytomegalovirus infection during pregnancy, cytomegalovirus proteins penetrate across the external membrane of placental villous syncytiotrophoblast and suppress activities of ATPase and Bcl-2 protein. Simultaneous increase in the content of annexin V and caspase 3 leads to structural disturbances in DNA in syncytiotrophoblast nuclei and stimulates their apoptosis. Structural abnormalities in the syncytiotrophoblast during exacerbation of cytomegalovirus infection are dangerous for fetal development.
机译:在妊娠期间巨细胞病毒感染加剧期间,巨细胞病毒蛋白穿透胎盘绒毛合体滋养层细胞的外膜并抑制ATPase和Bcl-2蛋白的活性。膜联蛋白V和caspase 3含量的同时增加导致合体滋养层细胞核中DNA的结构紊乱并刺激其凋亡。在巨细胞病毒感染恶化期间,合体滋养层细胞的结构异常对于胎儿发育是危险的。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号