Preparation of recombinant atoxic form of exotoxin A from pseudomonas aeruginosa

KaloshinA.A.; IsakovM.A.; MikhailovaN.A.; VertievJu.V.

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Preparation of recombinant atoxic form of exotoxin A from pseudomonas aeruginosa

机译：铜绿假单胞菌外毒素A重组无毒形式的制备

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Nucleotide sequences encoding full-length protein of Pseudomonas aeruginosa exotoxin A and its atoxic form were cloned and expressed in Escherichia coli cells. Purified recombinant exotoxin and immune rabbit sera protected mice from exotoxin A.

机译：克隆编码铜绿假单胞菌外毒素A全长蛋白及其无毒形式的核苷酸序列，并在大肠杆菌细胞中表达。纯化的重组外毒素和免疫兔血清可保护小鼠免受外毒素A的侵害。

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《Bulletin of experimental biology and medicine》 |2013年第3期|共5页
作者
KaloshinA.A.; IsakovM.A.; MikhailovaN.A.; VertievJu.V.;
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原文格式 PDF
正文语种 eng
中图分类基础医学;
关键词
antitoxin; exotoxin A; Pseudomonas aeruginosa; toxA gene;

机译：抗毒素;外毒素A;铜绿假单胞菌;toxA基因;

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专利

1. Preparation of recombinant atoxic form of exotoxin A from pseudomonas aeruginosa [J] . KaloshinA.A., IsakovM.A., MikhailovaN.A., Bulletin of experimental biology and medicine . 2013,第3期

机译：铜绿假单胞菌外毒素A重组无毒形式的制备
2. Isolation and characterizations of a novel recombinant scFv antibody against exotoxin A of Pseudomonas aeruginosa [J] . Zahra Shadman, Safar Farajnia, Mohammad Pazhang, BMC Infectious Diseases . 2021,第1期

机译：对铜绿假单胞菌的新重组SCFV抗体的分离与特征
3. Construction and recombinant expression of Pseudomonas aeruginosa truncated exotoxin A in Escherichia coli [J] . Qaiser Hina, Aslam Farheen, Iftikhar Saima, Cellular and molecular biology . 2018,第期

机译：铜绿假单胞菌的施工和重组表达截断Exotoxin A在大肠杆菌中
4. Preparation and epitope mapping of monoclonal antibodies to mex-a protein of mex-a, B/opr-m efflux pump in pseudomonas aeruginosa [C] . Masayuki Yamato, Hiroshi Yoneyama, Taiji nakae, 7th China-Japan International Congress of Microbiology Shanghai Symposium-2000 4-6 August 2000 Shanghai . 2000

机译：铜绿假单胞菌mex-a，B / opr-m外排泵mex-a蛋白单克隆抗体的制备及表位作图
5. Exploring the Therapeutic Potential of Pseudomonas aeruginosa Exotoxin A and Identifying Eukaryotic Factors Involved in its Intracellular Routing Pathway. [D] . Mohammed, Arshiya Fatima. 2015

机译：探索铜绿假单胞菌外毒素A的治疗潜力，并鉴定涉及其细胞内途径的真核因子。
6. Recombinant Pseudomonas exotoxin produced by cloning of Pseudomonas aeruginosa DNA in Escherichia coli having low toxicity to human or mice cells but retaining enzymatic activity giving cell-specific immunotoxin; vaccine application [O] . -1

机译：通过在大肠杆菌中克隆铜绿假单胞菌DNA产生的重组假单胞菌外毒素对人或小鼠细胞毒性低但保留酶活性提供细胞特异性免疫毒素;疫苗应用
7. The crystal structure of Pseudomonas aeruginosa exotoxin domain III with nicotinamide and AMP: conformational differences with the intact exotoxin. [O] . Li, M, Dyda, F, Benhar, I, 1995

机译：带有烟酰胺和AMP的铜绿假单胞菌外毒素结构域III的晶体结构：与完整外毒素的构象差异。
8. The Effect of Pseudomonas aeruginosa Exotoxin A on Antibody Forming Mouse Spleen Cells [R] . Pavlovskis, O. R., Wretlind, B., Hale, M. L. 1980

机译：铜绿假单胞菌外毒素a对小鼠脾细胞抗体形成的影响

Preparation of recombinant atoxic form of exotoxin A from pseudomonas aeruginosa

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