Long-term spatial memory retrieval at different times following formation in single session training in rats

摘要

The dynamics of retrieval of spatial memory formed in single-day training in rats was studied at different terms after training. Good learners, i.e. rats successfully learned to find the hidden platform in the Morris water maze after single-day training session, demonstrated spontaneous improvement of maze performance on day 5 after training in comparison with that in 24 h after training. Poor learners (maze performance during learning session did not differ from random level) demonstrated spontaneous improvement of maze performance by day 20 after training. These findings attest to the existence of multiple mechanisms of memory trace transformation at delayed terms after training.