Compaction Principle and Approaches to Biopolymer Structure Deciphering

摘要

On the basis of a principle of maximum compaction of biopolymer structure in a limited space derived from the concept about the existence of three different types of dimers in the studied structure, we propose a hypothesis according to which side groups in macromolecules (nitrogenous bases in nucleic acids or R-groups in proteins) are specifically distributed in different points depending on geometrical shape of dimer bending in the biopolymer chain backbone. The latter provides the possibility of complete deciphering of biopolymer structure.