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首页> 外文期刊>Bulletin of experimental biology and medicine >Effects of cytotoxins on intracellular na/K balance in mouse embryonic cell.
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Effects of cytotoxins on intracellular na/K balance in mouse embryonic cell.

机译:细胞毒素对小鼠胚胎细胞内na / K平衡的影响。

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摘要

Cytoplasmic Na/K imbalance induced by cytotoxic substances (ethylene glycol and cytochalasin B) was studied. Incubation in Dulbecco's medium with these cytotoxins caused changes in K and Na concentrations in the mouse two-cell embryo blastomer. The effects of both substances resulted in a drop of Na content in the embryonic cell. Washing from cytochalasin B restored the initial Na/K balance in the cytoplasm. Possible adaptive mechanisms involved in the regulation of intracellular ionic homeostasis are discussed.
机译:研究了由细胞毒性物质(乙二醇和细胞松弛素B)引起的细胞质Na / K失衡。将这些细胞毒素在Dulbecco培养基中孵育会导致小鼠两细胞胚胎卵裂球中K和Na的浓度发生变化。两种物质的作用都导致胚胎细胞中Na含量下降。从细胞松弛素B中洗涤可恢复细胞质中最初的Na / K平衡。讨论了调节细胞内离子稳态的可能的适应机制。

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