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首页> 外文期刊>Bulletin of experimental biology and medicine >Effect of histochrome on brain vessels and research and exploratory activity of senescence-accelerated OXYS rats.
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Effect of histochrome on brain vessels and research and exploratory activity of senescence-accelerated OXYS rats.

机译:组织色素对脑血管的影响以及衰老加速的OXYS大鼠的研究和探索活性。

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摘要

Changes in the diameter of brain vessels and intensity of collateral blood flow typical of chronic ischemia were detected by magnetic resonance imaging in senescence-accelerated OXYS rats demonstrating reduced (compared to Wistar rats) research and exploratory activity. Histochrome (antioxidant drug) produced positive effects on cerebral vessels in OXYS rats by stimulating collateral blood flow and acting as a vasodilator agent. Analysis of correlations showed that these effects of histochrome were closely related to its capacity to activate research and exploratory activity and reduce anxiety of OXYS rats in the open field test.
机译:通过磁共振成像检测衰老加速的OXYS大鼠的脑血管直径和侧支血流强度变化,证实了研究的减少(与Wistar大鼠相比)和探索性活动。组织色素(抗氧化剂)通过刺激侧支血流并充当血管扩张剂,对OXYS大鼠的脑血管产生积极影响。相关性分析表明,在露天试验中,组织色素的这些作用与其激活研究和探索活性以及减少OXYS大鼠焦虑症的能力密切相关。

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