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首页> 外文期刊>Bulletin of experimental biology and medicine >Role of neuropeptide Y in myocardial contractility of rats during early postnatal ontogeny.
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Role of neuropeptide Y in myocardial contractility of rats during early postnatal ontogeny.

机译:产后早期个体发育过程中神经肽Y在大鼠心肌收缩中的作用。

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摘要

We studied the effect of neuropeptide Y in concentrations of 10(-10)-10(-6) M on myocardial contractility of rats at the age of 7, 21, and 100 days. Studying the isometric contraction of myocardial strips showed that neuropeptide Y decreases the force of myocardial contraction in 7-day-old rat pups. Exogenous neuropeptide Y produced a biphasic effect in 21-day-old rats, which was manifested in the increase and subsequent decrease in myocardial contractility. Neuropeptide Y had little effect on myocardial contractility of 100-day-old animals.
机译:我们研究了浓度为10(-10)-10(-6)M的神经肽Y对7、21和100天龄大鼠心肌收缩力的影响。研究心肌条的等轴测收缩表明,神经肽Y降低了7天大的幼鼠的心肌收缩力。外源性神经肽Y在21天大的大鼠中产生了双相作用,表现为心肌收缩力的增加和随后的降低。神经肽Y对100日龄动物的心肌收缩力影响很小。

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