A decade of stem-cell research An interview with John Gearhart, Director of the Institute for Regenerative Medicine at the University of Pennsylvania, USA

摘要

EMBO reports (ER): It is now a decade since you and James Thomson, at the University of Madison–Wisconsin, both published your papers on the derivation of human stem cells from primordial germ cells and blastocysts, respectively (Shamblott et al, 1998; Thomson et al, 1998). There was, and still is, a great deal of hope that these cells will lead to cures for various severe diseases but, ten years later, how far are we in terms of practical therapies and applications?