首页> 外文期刊>Bulletin of experimental biology and medicine >Iron content and parameters of blood antioxidant activity in rats with hereditary arterial hypertension during experimental myocardial infarction.
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Iron content and parameters of blood antioxidant activity in rats with hereditary arterial hypertension during experimental myocardial infarction.

机译:实验性心肌梗死大鼠遗传性高血压中铁的含量和血液抗氧化活性参数

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摘要

Plasma, lymph and myocardial Fe(2+) contents and blood antioxidant activity were studied in hypertensive NISAG and normotensive Wistar rats with experimental myocardial infarction. In hypertensive rats, iron levels in plasma, lymph and myocardial tissue were increased throughout the experiment. In both strains iron content in the plasma during experimental myocardial infarction negatively correlated with blood antioxidant activity. In hypertensive NISAG rats this correlation persisted also during recovery. This attests to prooxidant effect of Fe(2+) aggravating the course of myocardial infarction in NISAG rats.
机译:在患有实验性心肌梗塞的高血压NISAG和血压正常的Wistar大鼠中研究了血浆,淋巴和心肌中Fe(2+)的含量以及血液中的抗氧化活性。在高血压大鼠中,在整个实验过程中血浆,淋巴和心肌组织中的铁水平均升高。在这两种菌株中,实验性心肌梗塞期间血浆中的铁含量与血液抗氧化活性呈负相关。在高血压NISAG大鼠中,这种相关性在恢复过程中也持续存在。这证明了Fe(2+)的促氧化作用加剧了NISAG大鼠的心肌梗塞进程。

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