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首页> 外文期刊>Bulletin of experimental biology and medicine >Effect of picrotoxin-induced seizures on lipid composition of cortical tissue homogenate and its nuclear fraction in rats.
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Effect of picrotoxin-induced seizures on lipid composition of cortical tissue homogenate and its nuclear fraction in rats.

机译:微小毒素引起的癫痫发作对大鼠皮质组织匀浆脂质组成及其核部分的影响。

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摘要

The content of lipids in rat cortical tissue homogenate and fraction of neuronal nuclei was determined under normal conditions and after picrotoxin-induced seizures. Changes in lipid composition of homogenate and nuclear fraction differed considerably. In homogenate, the content of sphingomyelin, lysophosphatidylcholine, and total phospholipids increased, while the content of free fatty acid remained unchanged; in the nuclear fraction the total phospholipid content decreased, while the concentration of free fatty acids increased.
机译:在正常条件下以及在微毒素诱导的癫痫发作之后,测定大鼠皮质组织匀浆中脂质的含量和神经元核的分数。匀浆和核部分脂质组成的变化差异很大。在匀浆中,鞘磷脂,溶血磷脂酰胆碱和总磷脂的含量增加,而游离脂肪酸的含量保持不变。在核部分中,总磷脂含量降低,而游离脂肪酸的浓度增加。

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