Visual detection of glucose using conformational switch of i-motif DNA and non-crosslinking gold nanoparticles

摘要

i-Motif tuned: Glucose is a ubiquitous fuel for metabolic pathways; its oxidation can trigger i-motif DNA formation. Using this unique conformational switch and non-crosslinking gold nanoparticles, a label-free colorimetric glucose sensor has been developed (see illustration).