首页> 外文期刊>Bulletin of experimental biology and medicine >Amino Acid composition of nephrophyt, a new complex plant preparation and its possible role in correction of mercuric chloride-induced acute renal failure in rats.
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Amino Acid composition of nephrophyt, a new complex plant preparation and its possible role in correction of mercuric chloride-induced acute renal failure in rats.

机译:肾病的氨基酸组成,一种新的复杂植物制剂及其在纠正氯化汞诱导的大鼠急性肾衰竭中的可能作用。

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摘要

Amino acid composition of a new Russian nephroprotective drug Nephrophyt (a complex mixture of dry plant extracts) was studied for the first time in order to validate its pharmacological effects in rats with mercuric chloride-induced nephropathy. The concentration of pyrrolidone amino acids and serine in this preparation was extremely high, which is uncommon for plant raw material. These data are in good correlation with pronounced nephroprotective effect and agree with published reports on pharmacological effects of individual amino acids and their metabolites. The prospects of the use of this preparation based on the data on its amino acid composition are discussed.
机译:为了验证其在氯化汞诱导的肾病大鼠中的药理作用,首次研究了一种新的俄罗斯肾脏保护药物肾植物(干燥植物提取物的复杂混合物)的氨基酸组成。该制剂中吡咯烷酮氨基酸和丝氨酸的浓度极高,这在植物原料中并不常见。这些数据与明显的肾保护作用具有良好的相关性,并且与有关单个氨基酸及其代谢产物的药理作用的已发表报告相一致。根据有关其氨基酸组成的数据,对该制剂的使用前景进行了讨论。

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