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首页> 外文期刊>Ecotoxicology >Integration of gene chip and topological network techniques to screen a candidate biomarker gene (CBG) for predication of the source water carcinogenesis risks on mouse Mus musculus.
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Integration of gene chip and topological network techniques to screen a candidate biomarker gene (CBG) for predication of the source water carcinogenesis risks on mouse Mus musculus.

机译:基因芯片和拓扑网络技术的集成,以筛选候选生物标记基因(CBG),以预测小鼠小家鼠源水致癌的风险。

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摘要

Screening of a candidate biomarker gene (CBG) to predicate the carcinogenesis risks in the Yangtze River source of drinking water in Nanjing area (YZR-SDW-NJ) on mouse (Mus musculus) was conducted in this research. The effects of YZR-SDW-NJ on the genomic transcriptional expression levels were measured by the GeneChip((R)) Mouse Genome and data treated by the GO database analysis. The 298 genes discovered as the differently expressed genes (DEGs) were down-regulated and their values were
机译:本研究进行了候选生物标记基因(CBG)的筛选,以预测小鼠(Mus musculus)南京地区长江饮用水源(YZR-SDW-NJ)的致癌风险。 YCR-SDW-NJ对基因组转录表达水平的影响通过GeneChip小鼠基因组进行测量,并通过GO数据库分析处理数据。被发现为差异表达基因(DEG)的298个基因被下调,其值是

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